The quality of a guideline The quality of a guideline (and essentially the recommendations it contains) can only be as good as the work and the effort that was put into it, when it was being constructed. A high quality guideline contains the following items: Systematic methods were used...
What is Real-World data? When working with evidencebased medicine we stride towards using randomized controlled trials of high quality to answer our questions. Yet, following a careful selection based on inclusion/exclusion criteria ect. how comparable are the results actually with what is going on in the real world? We...
Er du en del af et fagligt selskab eller fagligt miljø og har du et ønske om at udvikle evidensbaseret nationale kliniske retningslinjer? Så kan I nu via Sundhedsstyrelsen søge om puljemidler til dette. Se mere på Sundhedsstyrelsens hjemmeside. Ansøgningsfrist er d. 1 november 2018
The steps of a proper search Once you have formulated your PICO or PIRO question, you need to start looking for literature. When constructing a guideline, the initial search should focus on already existing guidelines and systematic reviews that potentially have already answered your question. If these do not...
If you want to make a recommendation on a new diagnostic test, then it is essential that you consider the potential of overdiagnosing. Overdiagnosing A substantial challenge with diagnostic tests are that there is a risk that you may diagnose a patient with a disease, that may never have...
Regardless of whether you want to assess the effect of an intervention or rather would like to investigate the effectiveness of a new diagnostic test, the universal rule is, that your question needs to be as specific as possible. The question that you want to ask, needs to specify...
The backbone of your systematic review or guideline are the questions that you seek to answer. The questions should reflect a central, clinical issue and these should be formulated prior to going through the literature. The questions constitute the foundation on which studies to select (inclusion – and exclusion...
Evidence-synthesis: Yes, it is important 18. January 2020
Using GRADE to assess the quality of preclinical research 29. March 2019
Missing data in diagnostic accuracy studies – what to do? 29. March 2019
Pulje til udvikling af Nationale Kliniske Retningslinjer (NKR) (danish only) 18. March 2019
Something new for your toolbox – Cochrane Risk of Bias 2.0 19. January 2019
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