There is immense amount of preclinical research being conducted every day, all with the goal to potentially improve clinical practice. Preclinical research has its pros and cons compared to clinical work. On the positive side, it allows you to thoroughly assess pathophysiological mechanisms, to evaluate potential harm and to...
Evaluating the methodological construction of a guideline is one thing, but what about the clinical credibility and implementability of a guideline? A previous review by Kastner et al 2015 showed that how guidelines are developed and written essentially influences how often they are being used. The review goes through...
The following is a podcast on what influence research has on society from the center for Evidence-Based Medicine in Oxford. Is the research being done actually useful and does it have an impact? What is the difference between academic and societal impact? Here are some food for thought. Research...
Evidence-based recommendations are constructed to aid decision-making, by combining the available evidence with clinical practice. However, when the evidence is low to very low, this often results in weak recommendations. In a medical situation, getting a straight answer is essential, so the questions arises – are these kind...
- Using GRADE to assess the quality of preclinical research 29. March 2019
- Missing data in diagnostic accuracy studies – what to do? 29. March 2019
- Pulje til udvikling af Nationale Kliniske Retningslinjer (NKR) (danish only) 18. March 2019
- Something new for your toolbox – Cochrane Risk of Bias 2.0 19. January 2019
- The Evidence Ecosystem – reducing waste of evidence 6. December 2018
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